Searchable abstracts of presentations at key conferences in endocrinology

ea0025p28 | Clinical biochemistry | SFEBES2011

25OH vitamin D analysis by liquid chromatography tandem mass spectrometry: interpret results with caution

Wright Michael , Taylor Kevin , Mawson Deborah , Grace Phillip , Halsall David

Liquid chromatography tandem mass spectrometry (LC–MS/MS) methods are considered superior to immunoassay for the analysis of serum 25-hydroxy vitamin D (25-OHD) due to improved performance and potential cost benefits. As LC–MS/MS is appropriate for the analysis of other clinically relevant hormones tandem mass spectrometers are becoming commonplace in UK clinical laboratories. However, like immunoassay, LC–MS/MS methods are not foolproof and inappropriate use of...